Hepatitis B vaccine prepared by culturing genetically-engineered Hansenula polymorpha yeast cells with a Recombinant DNA technology. Produces stable recombinant strains, and higher productivity. Immunogenic and safe, free from any material of human or animal origin. In Chronic Renal Failure patients, induces a high immunogenicity and low reactogenicity. Licensed in 50 countries with more than 250 million doses distributed worldwide. Hepatitis B vaccine can be safely and effectively given simultaneously but at different injection site with DTP, DT, TT, BCG, Measles, Polio vaccine (OPV and IPV) and yellow fever vaccine.

Sii Hepatitis B Vaccine (rDNA) – Pediatric

Dosage: 10 mcg in 0.5 ml

Delaying the birth dose results in an increased risk of HBV infection.

Presentation

0.5 ml – single dose ampoule

0.5 ml – single dose vial

5 ml – 10 dose vial

Route of administration

Intramuscular

Dosage schedules

6-10-14 weeks

0-1-6 months

0-1-2 months (rapid schedule) recommended for neonates born of mothers who are HBV carriers or in circumstances with known exposure to HBV.

Sii Hepatitis B Vaccine (rDNA) – Adult

Dosage: 20 mcg in 1 ml

Presentation

1 ml – single dose ampoule

1 ml – single dose vial

10 ml – 10 dose vial

Route of administration

Intramuscular

Dosage schedules

0-1-6 months

0-1-2-6 months (4 doses of 40 mcg): for chronic haemodialysis patients or persons with an impaired immune system.