Ready to use Hexavalent Vaccine

Diphtheria, Tetanus, Pertussis (Whole Cell), Hepatitis B (rDNA), Poliomyelitis (Inactivated) and Haemophilus influenzae Type b Conjugate Vaccine (Adsorbed).

Therapeutic Indications

HEXASIIL® is indicated for active immunization of infants, at or above the age of 6 weeks against Diphtheria, Tetanus, Pertussis, Hepatitis B, Poliomyelitis and invasive diseases caused by Haemophilus influenzae type b for 3 dose regimen (6, 10 & 14 Weeks) for primary vaccination and booster dose at the age of 12-24 months.

Primary Vaccination

For active immunization of infants, it is recommended that 3 doses of 0.5 ml to be administered with an interval of at least four weeks between doses starting at six weeks of age.

In countries, where peri-natal transmission of hepatitis B virus (HBV) is common, the first dose of Hepatitis B should be given as soon as possible after birth. In this case, the HEXASIIL® can be used to complete the primary series from 6 weeks of age.

Booster Vaccination

A booster dose of DTP, Hib and IPV should be given preferably during the second year of life (≥ 6 months after last primary dose). Booster doses should be given in accordance with the official recommendations.

Method of Administration

The HEXASIIL® liquid vaccine vial/PFS should be shaken before use to homogenize the suspension. HEXASIIL® should be administered intramuscularly. The recommended injection sites are generally the antero-lateral aspect of the upper thigh in infants and toddlers. Do not administer by intravascular, intradermal or subcutaneous injection.

Pharmaceutical Form / Presentation

Single dose presentation: 1 dose vial of 0.5 ml.

Multi-dose presentation: 10 dose vial of 5 ml.

HEXASIIL® is a pinkish to yellowish turbid liquid in which the Aluminium Phosphate adjuvant tends to settle down slowly on storage.

Shelf-life
Unopened vial: shelf-life is 24 months.

Opened multidose vial: After first opening, the vaccine can be used for up to 28 days, provided it is stored between +2ºC to +8ºC.

Storage

Store in a refrigerator (+2ºC to +8ºC). Do not freeze. Discard vaccine if frozen. Keep the vaccine in the outer carton in order to protect from light.